The Hidden DNA Loops That Help Tumors Evade Treatment

Pancreatic cancer’s deadly resilience may be tied to extrachromosomal DNA, which allows tumor cells to rapidly adapt to stress and evade treatment. These circular DNA fragments carry extra copies of oncogenes like MYC, fueling aggressive growth and making some cancer cells nearly unstoppable. Scientists found that these DNA rings enable tumors to morph dynamically, switching [...]

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