New Method Detects Ligand-Protein Interactions With Unprecedented Sensitivity

PELSA is a sensitive, versatile method for identifying ligand-binding proteins and sites in native systems without requiring ligand modification. It outperforms traditional approaches in sensitivity, especially for low-affinity metabolite interactions, and offers broad applications in drug design and biological studies. A research team led by Prof. Mingliang Ye from the Dalian Institute of Chemical Physics, [...]

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